购物车
- 全部删除
您的购物车当前为空
Anti-VLDLR Antibody (3U184)
还可以产品编号 TMAY-01596
Anti-VLDLR Antibody (3U184) 是一种 Mouse 抗体，靶向 VLDLR。Anti-VLDLR Antibody (3U184) 可用于 ELISA。
Anti-VLDLR Antibody (3U184)
Anti-VLDLR Antibody (3U184)
还可以产品编号 TMAY-01596
Anti-VLDLR Antibody (3U184) 是一种 Mouse 抗体，靶向 VLDLR。Anti-VLDLR Antibody (3U184) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-VLDLR Antibody (3U184) is a Mouse antibody targeting VLDLR. Anti-VLDLR Antibody (3U184) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3U184 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VLDLR / VLDL Receptor (rh VLDLR / VLDL Receptor; TMPY-01085; NP_003374.3; Met 1-Ser 797). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is abundant in heart, skeletal muscle, also ovary and kidney, but not in liver. VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR mediates the phosphorylation of mDab1 (mammalian disabled protein) via binding to Reelin, and induces the modulation of Tau phosphorylation. This pathway regulates the migration of neurons along with the radial glial fiber network during brain development. Defects of VLDLR may be the cause of VLDLR-associated cerebellar hypoplasia (VLDLRCH), a syndrome characterized by moderate-to-profound mental retardation, delayed ambulation, and predominantly truncal ataxia. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human VLDLR / VLDL Receptor protein (TMPY-01085) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-VLDLR Antibody (3U184) | purchase Anti-VLDLR Antibody (3U184) | Anti-VLDLR Antibody (3U184) cost | order Anti-VLDLR Antibody (3U184)
嗨！有任何问题？点我咨询
评论内容