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Anti-CXCR2 Polyclonal Antibody 2

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Anti-CXCR2 Polyclonal Antibody 2
产品编号 TMAB-00507

Anti-CXCR2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CXCR2。Anti-CXCR2 Polyclonal Antibody 2 可用于 WB。

Anti-CXCR2 Polyclonal Antibody 2

Anti-CXCR2 Polyclonal Antibody 2

Rating icon 还可以
Anti-CXCR2 Polyclonal Antibody 2
产品编号 TMAB-00507

Anti-CXCR2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CXCR2。Anti-CXCR2 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CXCR2 Polyclonal Antibody 2 is a Rabbit antibody targeting CXCR2. Anti-CXCR2 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Sample:
Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 μg
Lane 2: U937 (Human) Cell Lysate at 30 μg
Primary: Anti-CXCR2 (TMAB-00507) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45/55 kDa
Observed band size: 59 kDa
2. Sample:
Lane 1: Human THP-1 cell lysates
Lane 2: Human U937 cell lysates
Lane 3: Human HL60 cell lysates
Lane 4: Human HepG2 cell lysates
Primary: Anti-CXCR2 (TMAB-00507) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 55 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CXCR2
抗原种属
Human
基因ID
3579
Uniprot ID
P25025
研究领域
GPCR,SARS Coronavirus,Other cell division antibodies
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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