规格

价格

库存

数量

100 mg

待询

500 mg

待询

生物活性

产品描述

RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice.

体内活性

RC-3095 impairs aversive but not recognition memory in Wistar male rats [1]. RC-3095 (0.3 mg/kg or 1 mg/kg; S.C.) shows anti-inflammatory effects in 2 experimental models of arthritis, collagen-induced arthritis, and antigen-induced arthritis. Arthritic mice treated with RC-3095 show a significant reduction in the concentrations of IL-1, IL-17, and TNF, and showed a diminished expression of GRPR [2].

化学信息

分子量	1166.396
分子式	C₅₈H₈₃N₁₅O₁₁
CAS No.	162666-31-1
Smiles	CC(O)=O.CC(C)C[C@@H](CN[C@@H](CC(C)C)C(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1Cc2c(CN1)[nH]c1ccccc21)C(C)C
密度	1.31g/cm3