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Anti-Podoplanin Antibody (9C226)
还可以产品编号 TMAY-03195
Anti-Podoplanin Antibody (9C226) 是一种 Rabbit 抗体，靶向 Podoplanin。Anti-Podoplanin Antibody (9C226) 可用于 IHC-P。
Anti-Podoplanin Antibody (9C226)
Anti-Podoplanin Antibody (9C226)
还可以产品编号 TMAY-03195
Anti-Podoplanin Antibody (9C226) 是一种 Rabbit 抗体，靶向 Podoplanin。Anti-Podoplanin Antibody (9C226) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Podoplanin Antibody (9C226) is a Rabbit antibody targeting Podoplanin. Anti-Podoplanin Antibody (9C226) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9C226 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Immunochemical staining of mouse PDPN in mouse kidney with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse PDPN in mouse brain with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:250-1:1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Podoplanin / PDPN (rM Podoplanin / PDPN; TMPY-02659; NP_034459.2; Met1-Lys133). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.PDPN is a mucin-type glycoprotein negatively charged by extensive O-glycosylation and a high content of sialic acid, which expresses the adhesive property. It is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. PDPN may contribute to form odontoblastic fiber or function as the anchorage to the tooth development and in proliferating epithelial cells of cervical loop and apical bud. The intensity of podoplanin expression is negatively correlated with the expression of CD34 and factor VIII. Podoplanin would be useful as a diagnostic marker for epithelioid hemangioendothelioma in liver tumors.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Podoplanin / PDPN Protein (TMPY-02659) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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