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Anti-CENPC Antibody (3X906)

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Anti-CENPC Antibody (3X906)
产品编号 TMAC-00815
别名 MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C

Anti-CENPC Antibody (3X906) 是一种 Rabbit 抗体,靶向 CENPC。Anti-CENPC Antibody (3X906) 可用于 WB,ICC,IF,IHC,FCM,IP。

Anti-CENPC Antibody (3X906)

Anti-CENPC Antibody (3X906)

Rating icon 还可以
Anti-CENPC Antibody (3X906)
产品编号 TMAC-00815 别名 MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C

Anti-CENPC Antibody (3X906) 是一种 Rabbit 抗体,靶向 CENPC。Anti-CENPC Antibody (3X906) 可用于 WB,ICC,IF,IHC,FCM,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CENPC Antibody (3X906) is a Rabbit antibody targeting CENPC. Anti-CENPC Antibody (3X906) can be used in WB,ICC,IF,IHC,FCM,IP.
别名MIF2, Interphase centromere complex protein 7, ICEN7, hcp-4, Centromere protein C 1, Centromere protein C, Centromere autoantigen C1, Centromere autoantigen C, CENPC1, CENPC_HUMAN, CENP-C 1, CENP-C
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of CENPC on K562 cell lysate using anti-CENPC antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-CENPC antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins.
3. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-CENPC antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins.
4. ICC staining CENPC in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of K562 cells with CENPC antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; IP: 1:10-50; FCM: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The evolutionarily conserved Centromere Protein-C, CENP-C, is a kinetochore assembly protein. CENP-C is located on the fibers of the kinetochore and constitutes a kinetochore organizing center that tightly associates with DNA. CENP-C is necessary for the formation of a functional centromere, which indicates that CENP-C is important for mitotic progression. In addition, CENP-C is lost from centromeres during herpes simplex virus 1 infection, causing substantial structural changes in the kinetochore, which suggests that the structure of CENP-C is regulated during the cell cycle.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: human CENPC aa 400-600
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 107 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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