Name: Tabituximab
Brand: TargetMol
SKU: T77449
Price: 2900 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 2,900

现货

5 mg

¥ 11,490

现货

10 mg

¥ 19,140

现货

25 mg

¥ 34,460

现货

生物活性

产品描述	Tabituximab (ONC-005) is a humanized monoclonal antibody that targets FZD10 (FZD10), a Wnt receptor, and exhibits antitumor activity. Tabituximab binds to FZD10 on the surface of tumor cells, blocking the binding of Wnt ligands to the receptor, thereby inducing tumor cell apoptosis and inhibiting tumor invasion and metastasis. Tabituximab can be used in research on tumors and immune system diseases.
体外活性	非放射标记的 Tabituximab 抗体对滑膜肉瘤细胞的生长仅表现出较弱的抑制作用。[1]
体内活性	经过钇-90 放射标记的 Tabituximab 在小鼠异种移植模型中通过单次静脉注射后则展现出显著的抗肿瘤效果。[1]
别名	坦比妥昔单抗, OTSA101, OTSA 101, ONC-005, ONC005
反应种属	Human
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	144.63 kDa
CAS No.	1644134-10-0

储存&溶解度

存储	-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Tabituximab