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顶部产品介绍化学信息储存和溶解信息计算器技术支持

GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

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货号 TMPK-01320

别名 GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.7 kDa and the accession number is XP_015304775.2.

GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
其他形式的 “GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated”:
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated
GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc)
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)

GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-01320 别名 GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.7 kDa and the accession number is XP_015304775.2.

规格价格库存数量
5 μg
¥ 643
6-8日内发货
10 μg
¥ 1,050
6-8日内发货
20 μg
¥ 1,760
5日内发货
50 μg
¥ 3,480
5日内发货
100 μg
¥ 5,930
5日内发货
200 μg
¥ 10,700
5日内发货
500 μg
¥ 23,700
5日内发货
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产品介绍

生物活性
产品描述
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.7 kDa and the accession number is XP_015304775.2.
生物活性
Immobilized Cynomolgus GDF15, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 76.3ng/ml determined by ELISA.
研究背景
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
种属
Cynomolgus
表达系统
HEK293 Cells
标签N-His-Avi
蛋白编号XP_015304775.2
蛋白构建Gln20-Glu351
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in 20 mM PB, 400 mM NaCl (pH 6.0).
别名GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量40.7 kDa (predicted). Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

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关键词

GFR a-like
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