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Anti-CD3 epsilon/CD3e Antibody (9X587)

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货号 TMAB-00353

别名 CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e

Anti-CD3 epsilon/CD3e Antibody (9X587) 是一种 Mouse 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody (9X587) 可用于 FCM。

Anti-CD3 epsilon/CD3e Antibody (9X587)

Anti-CD3 epsilon/CD3e Antibody (9X587)

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货号 TMAB-00353 别名 CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e

Anti-CD3 epsilon/CD3e Antibody (9X587) 是一种 Mouse 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Antibody (9X587) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,870
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产品介绍

生物活性
产品描述
Anti-CD3 epsilon/CD3e Antibody (9X587) is a Mouse antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody (9X587) can be used in FCM.
别名CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e
Ig Type
Mouse IgG2a, k
克隆号
9X587
反应种属
Human
验证活性
scatter diagram showing peripheral blood lymphocytes stained with CD3 The cells were incubated with the antibody (TMAB-00353, 1 µg/Test) for 30 min at room temperature. The secondary antibody used for 40 min at room temperature.Acquisition of >20,000 events was performed.
verifiedActivity
应用FCM
推荐剂量
FCM: 1ug/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M PBS (pH7.4).
研究背景CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD3
抗原种属
Human
基因名称
CD3E
基因ID
916
蛋白名称
T-cell surface glycoprotein CD3 epsilon chain
Uniprot ID
P07766
研究领域
Regulatory T Cells,CD,cd3,Human Lineage Negative
功能
The CD3 complex mediates signal transduction.
化学信息
分子量Theoretical: 20 kDa. Actual: 20 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器

关键词

CD3-TCR complexCD3e molecule, epsilon
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