Name: BIM-23190
Brand: TargetMol
SKU: T39262
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 10,600

6-8周

生物活性

产品描述	BIM-23190 is a somatostatin analog that acts as a selective agonist for SSTR2 and SSTR5 receptors. It displays potency with K i values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 finds utility in cancer and acromegaly research.
体外活性	BIM-23190 tends to mildly stimulate PRL secretion[1].
体内活性	BIM-23190 (50 μg/mouse, twice a day) exhibits significant anti-tumor (C6 glioma) activity[2]. Animal Model: Male athymic nude (nu/nu) mice, 5-6 wk old (C6 glioma)[2]. Dosage: 50 μg/mouse Administration: Injected twice a day for 19 days. Result: Significantly reduced the tumor growth rate.

化学信息

分子量	1202.46
分子式	C₅₇H₇₉N₁₃O₁₂S₂
CAS No.	182153-96-4
Sequence	{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-Cys-Tyr-{D-Trp}-Lys-{Abu}-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7)
Sequence Short	{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-CY-{D-Trp}-K-{Abu}-CT-NH2 (Disulfide bridge: Cys2-Cys7)