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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD89 Antibody (5P664)

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货号 TMAY-03684

别名 XXbac-BPG230H20.5, FcαRI, FCAR, FcalphaRI, Fc fragment of IgA receptor, CTB-61M7.2, CD89

Anti-CD89 Antibody (5P664) 是一种 Rabbit 抗体，靶向 CD89。Anti-CD89 Antibody (5P664) 可用于 ELISA。

Anti-CD89 Antibody (5P664)

Anti-CD89 Antibody (5P664)

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货号 TMAY-03684 别名 XXbac-BPG230H20.5, FcαRI, FCAR, FcalphaRI, Fc fragment of IgA receptor, CTB-61M7.2, CD89

Anti-CD89 Antibody (5P664) 是一种 Rabbit 抗体，靶向 CD89。Anti-CD89 Antibody (5P664) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD89 Antibody (5P664) is a Rabbit antibody targeting CD89. Anti-CD89 Antibody (5P664) can be used in ELISA.
别名XXbac-BPG230H20.5, FcαRI, FCAR, FcalphaRI, Fc fragment of IgA receptor, CTB-61M7.2, CD89
Ig Type
Rabbit IgG
克隆号
5P664
反应种属
Rat
特异性
Rat CD89/FCAR
No cross-reactivity in ELISA with
Rat FCGR1a
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD89 / FCAR (rR CD89 / FCAR; TMPY-02071; NP_973721.1; Met1-Asn228).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This receptor is present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, especially phagocytes located in mucosal areas. Upon ligand IgA binding, FcαRI associates with the FcR γ signaling molecule bearing the immunoreceptor tyrosine-based activation motif (ITAM) through a unique charge-based mechanism and triggers multiple cell-mediated immune responses. It has been reported that Fc RI is a dual-function receptor that can mediate both inflammatory and anti-inflammatory responses depending on the type of interaction with its ligand. Sustained aggregation of FCAR results in activation of target-cell functions such as antigen presentation and cytokine release. In contrast, Monomeric targeting with serum IgA or with a variety of anti-FcαRI Fab fragments triggers an inhibitory response and additionally induces apoptosis. FcαRI thus play an fundamental role in preventing tumor development and growth, as well as in controlling inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat CD89 / FCAR protein (TMPY-02071)
抗原种属
Rat
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules, Fc Receptors
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

  • 稀释 计算器

关键词

CD-89CD 89
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