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Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 343 | 6-8日内发货 | |
| 10 μg | ¥ 549 | 6-8日内发货 | |
| 20 μg | ¥ 898 | 5日内发货 | |
| 50 μg | ¥ 1,760 | 5日内发货 | |
| 100 μg | ¥ 2,960 | 5日内发货 | |
| 200 μg | ¥ 5,350 | 5日内发货 | |
| 500 μg | ¥ 11,800 | 5日内发货 |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 产品描述 | Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025. |
| 种属 | Mouse |
| 表达系统 | E. coli |
| 标签 | N-His |
| 蛋白编号 | P12025 |
| 别名 | NEGF2,MKARAP,MK1,MK,MEK,MDK,ARAP |
| 蛋白构建 | Lys23-Asp140 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 分子量 | 14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result. |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as 0.22 μm filtered solution in PBS, 350 mM NaCl, 200 mM L-arginine (pH 7.4). |
| 存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. |