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MRTFA Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 25.4 kDa and the accession number is Q969V6.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 656 | 20日内发货 | |
| 10 μg | ¥ 1,070 | 20日内发货 | |
| 20 μg | ¥ 1,800 | 20日内发货 | |
| 50 μg | ¥ 2,730 | 20日内发货 | |
| 100 μg | ¥ 3,760 | 20日内发货 | |
| 200 μg | ¥ 5,780 | 20日内发货 | |
| 500 μg | ¥ 9,870 | 20日内发货 | |
| 1 mg | ¥ 16,000 | 20日内发货 |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 产品描述 | MRTFA Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 25.4 kDa and the accession number is Q969V6. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6xHis-KSI |
| 蛋白编号 | Q969V6 |
| 别名 | Myocardin-related transcription factor A,MRTF-A,MRTFA,MKL1,MKL/myocardin-like protein 1,Megakaryocytic acute leukemia protein,Megakaryoblastic leukemia 1 protein,MAL,KIAA1438 |
| 氨基酸序列 | LHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKE |
| 蛋白构建 | 400-500 aa |
| 蛋白纯度 | > 85% as determined by SDS-PAGE. |
| 分子量 | 25.4 kDa (predicted) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 缓冲液 | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus. |