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Anti-CD93/C1qR1 Antibody-PE (8N985)
还可以产品编号 TMAY-02387P
Anti-CD93/C1qR1 Antibody-PE (8N985) 是一种 PE-conjugated Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody-PE (8N985) 可用于 FCM。
Anti-CD93/C1qR1 Antibody-PE (8N985)
Anti-CD93/C1qR1 Antibody-PE (8N985)
还可以产品编号 TMAY-02387P
Anti-CD93/C1qR1 Antibody-PE (8N985) 是一种 PE-conjugated Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody-PE (8N985) 可用于 FCM。
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| 产品描述 | Anti-CD93/C1qR1 Antibody-PE (8N985) is a PE-conjugated Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody-PE (8N985) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 8N985 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD93 expression on human whole blood monocytes. Cells were stained with PE-conjugated anti-Human CD93. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93 / C1qR (rh CD93 / C1qR; TMPY-02268; Q9NPY3; Met1-Lys580) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD93 / C1qR Protein (TMPY-02268) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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