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Anti-IL-2 R gamma/CD132 Antibody (6X102)

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产品编号 TMAY-00965

Anti-IL-2 R gamma/CD132 Antibody (6X102) 是一种 Mouse 抗体,靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody (6X102) 可用于 ELISA。

Anti-IL-2 R gamma/CD132 Antibody (6X102)

Anti-IL-2 R gamma/CD132 Antibody (6X102)

Rating icon 还可以
产品编号 TMAY-00965

Anti-IL-2 R gamma/CD132 Antibody (6X102) 是一种 Mouse 抗体,靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody (6X102) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-IL-2 R gamma/CD132 Antibody (6X102) is a Mouse antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody (6X102) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG2a
克隆号
6X102
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD132 / IL2RG (rh CD132 / IL2RG; P31785)Met1-Asn254). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor subunit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15, and the interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (X-SCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor based on chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why a deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human CD132 / IL2RG Protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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