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Anti-I-309/CCL1 Antibody (1S849)

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产品编号 TMAY-00196
别名 TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1

Anti-I-309/CCL1 Antibody (1S849) 是一种 Mouse 抗体,靶向 I-309/CCL1。Anti-I-309/CCL1 Antibody (1S849) 可用于 ELISA。

Anti-I-309/CCL1 Antibody (1S849)

Anti-I-309/CCL1 Antibody (1S849)

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产品编号 TMAY-00196 别名 TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1

Anti-I-309/CCL1 Antibody (1S849) 是一种 Mouse 抗体,靶向 I-309/CCL1。Anti-I-309/CCL1 Antibody (1S849) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 585
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100 μL
¥ 1,689
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产品介绍

生物活性
产品描述
Anti-I-309/CCL1 Antibody (1S849) is a Mouse antibody targeting I-309/CCL1. Anti-I-309/CCL1 Antibody (1S849) can be used in ELISA.
别名TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1
Ig Type
Monoclonal Mouse IgG2a
克隆号
1S849
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human I-309/CCL1 (rh I-309/CCL1; TMPY-00695; NP_002972.1; Lys24-Lys96). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferation, apoptosis and adhesion. It has been demonstrated that I-309/CCL1/TCA-3 displays chemotactic activity for monocytes and other cell types such as NK cells and dendritic cells, but not for neutrophils. Furthermore, as the only known physiological ligand for CCR8, I-309/CCL1/TCA-3 was identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. I-309/CCL1/TCA-3 induces significant levels of LTC4 from elicited eosinophils.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human I-309/CCL1 Protein (TMPY-00695)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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