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别名 TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1
Anti-I-309/CCL1 Antibody (1S849) 是一种 Mouse 抗体,靶向 I-309/CCL1。Anti-I-309/CCL1 Antibody (1S849) 可用于 ELISA。
Anti-I-309/CCL1 Antibody (1S849) 是一种 Mouse 抗体,靶向 I-309/CCL1。Anti-I-309/CCL1 Antibody (1S849) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 585 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
| 产品描述 | Anti-I-309/CCL1 Antibody (1S849) is a Mouse antibody targeting I-309/CCL1. Anti-I-309/CCL1 Antibody (1S849) can be used in ELISA. |
| 别名 | TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1 |
| Ig Type | Mouse IgG2a |
| 克隆号 | 1S849 |
| 交叉反应 | Human |
| 特异性 | Human I-309/CCL1 |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human I-309/CCL1 (rh I-309/CCL1; TMPY-00695; NP_002972.1; Lys24-Lys96). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferation, apoptosis and adhesion. It has been demonstrated that I-309/CCL1/TCA-3 displays chemotactic activity for monocytes and other cell types such as NK cells and dendritic cells, but not for neutrophils. Furthermore, as the only known physiological ligand for CCR8, I-309/CCL1/TCA-3 was identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. I-309/CCL1/TCA-3 induces significant levels of LTC4 from elicited eosinophils. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human I-309/CCL1 Protein (TMPY-00695) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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