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Anti-TACI Antibody (1S494) 是一种 Rabbit 抗体,靶向 TACI。Anti-TACI Antibody (1S494) 可用于 ELISA。
Anti-TACI Antibody (1S494) 是一种 Rabbit 抗体,靶向 TACI。Anti-TACI Antibody (1S494) 可用于 ELISA。
产品描述 | Anti-TACI Antibody (1S494) is a Rabbit antibody targeting TACI. Anti-TACI Antibody (1S494) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1S494 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TACI / TNFRSF13B / CD267 (rh TACI / TNFRSF13B / CD267; TMPY-02096; O14836-2; Ser2-Thr120). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF13B is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. TACI/TNFRSF13B/CD267 induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. |
偶联 | Unconjugated |
免疫原 | Recombinant Human TACI / TNFRSF13B / CD267 Protein (TMPY-02096) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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