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Anti-CD31/PECAM-1 Antibody (8Z378) 是一种 Rabbit 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (8Z378) 可用于 ELISA,IHC-P。
Anti-CD31/PECAM-1 Antibody (8Z378) 是一种 Rabbit 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (8Z378) 可用于 ELISA,IHC-P。
产品描述 | Anti-CD31/PECAM-1 Antibody (8Z378) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (8Z378) can be used in ELISA,IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8Z378 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human CD31 in human mesenteric tumor with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. 2. Immunochemical staining of human CD31 in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. |
应用 | ELISA,IHC-P |
推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD31 / PECAM1 (rh CD31 / PECAM1; TMPY-00970; EAW94208.1; Met 1-Lys 601). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD31 / PECAM1 protein (TMPY-00970) |
抗原种属 | Human |
研究领域 | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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