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Anti-LRP1 Antibody (1R508) 是一种 Rabbit 抗体,靶向 LRP1。Anti-LRP1 Antibody (1R508) 可用于 ELISA, WB, IHC。
Anti-LRP1 Antibody (1R508) 是一种 Rabbit 抗体,靶向 LRP1。Anti-LRP1 Antibody (1R508) 可用于 ELISA, WB, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,305 | 5日内发货 | |
100 μL | ¥ 2,190 | 5日内发货 |
产品描述 | Anti-LRP1 Antibody (1R508) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (1R508) can be used in ELISA, WB, IHC. |
别名 | TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR |
Ig Type | Rabbit IgG |
克隆号 | 1R508 |
交叉反应 | Human, Mouse, Rat |
验证活性 | 1. Western Blot -Positive WB detected in: Mouse lung tissue lysate, Rat liver tissue lysate -All lanes: LRP1 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 505 kDa -Observed band size: 100 kDa 2. IHC image of TMAH-00704 diluted at 1:150 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody. 3. IHC image of TMAH-00704 diluted at 1:150 and staining in paraffin-embedded mouse brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody. |
应用 | ELISA, WB, IHC |
推荐剂量 | WB:1:500-1:2000; IHC:1:50-1:200. |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | [Low-density lipoprotein receptor-related protein 1 85 kDa subunit]: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 515 kDa subunit]: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 intracellular domain]: Cytoplasm. Nucleus.; Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human LRP1 |
抗原种属 | Human |
基因ID | 4035 |
Uniprot ID | |
研究领域 | Neuroscience, Cancer, Cardiovascular, Cell biology, Metabolism, Signal transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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