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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ATP13A2 Polyclonal Antibody

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货号 TMAB-02939

Anti-ATP13A2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ATP13A2。Anti-ATP13A2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ATP13A2 Polyclonal Antibody

Anti-ATP13A2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02939

Anti-ATP13A2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ATP13A2。Anti-ATP13A2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ATP13A2 Polyclonal Antibody is a Rabbit antibody targeting ATP13A2. Anti-ATP13A2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein (By similarity). Lysosome.
组织特异性Expressed in brain; protein levels are markedly increased in brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout the cingulate cortex (at protein level). In the substantia nigra, it is found in neuromelanin-positive dopaminergic neurons (at protein level).
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ATP13A2 is a 1,180 amino acid multi-pass membrane protein that belongs to the P5 subfamily of ATPases which play an important role in the transportation of inorganic cations. Expressed as multiple alternative spliced isoforms, ATP13A2 functions to catalyze the conversion of ATP to ADP and a free phosphate, thereby participating in the active transport of ions across cellular membranes. Defects in the gene encoding ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS), a rare hereditary type of Parkinson’s disease that exhibits juvenile onset and is characterized by neurodegeneration and dementia. The ATP13A2 gene maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ATP13A2
抗原种属
Human
基因名称
ATP13A2
基因ID
23400
蛋白名称
Polyamine-transporting ATPase 13A2
Uniprot ID
Q9NQ11
功能
May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity.
化学信息
分子量Theoretical: 129 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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