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Anti-HAS1 Polyclonal Antibody
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产品编号 TMAB-00829
别名 Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1
Anti-HAS1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HAS1。Anti-HAS1 Polyclonal Antibody 可用于 WB。
Anti-HAS1 Polyclonal Antibody
Anti-HAS1 Polyclonal Antibody
还可以产品编号 TMAB-00829 别名 Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1
Anti-HAS1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HAS1。Anti-HAS1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
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抗原信息
化学信息
| 产品描述 | Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB. |
| 疾病造模方案 | |
| 别名 | Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat (predicted:Pig,Cow,Sheep) |
| 验证活性 | Sample: Lane 1: Mouse Testis Lysates Lane 2: Mouse Spleen Lysates Lane 3: Rat Testis Lysates Lane 4: Rat Spleen Lysates Lane 5: Human U-87 MG cell Lysates Lane 6: Human DU145 cell Lysates Primary: Anti-HAS1 (TMAB-00829) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 65 kDa Observed band size: 65 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Multi-pass membrane protein |
| 组织特异性 | Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells. |
| 免疫原 | KLH conjugated synthetic peptide: human Hyaluronan synthase 1 |
| 抗原种属 | Human |
| 基因名称 | HAS1 |
| 基因ID | |
| 蛋白名称 | Hyaluronan synthase 1 |
| Uniprot ID | |
| 研究领域 | Extracellular Matrix,Stem cells,Axis formation and symmetry,ECM Proteins,Neurogenesis,Other Enzymes |
| 功能 | Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate. |
| 分子量 | Theoretical: 65 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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