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Anti-HAS1 Polyclonal Antibody

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货号 TMAB-00829

别名 Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1

Anti-HAS1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HAS1。Anti-HAS1 Polyclonal Antibody 可用于 WB。

Anti-HAS1 Polyclonal Antibody

Anti-HAS1 Polyclonal Antibody

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货号 TMAB-00829 别名 Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1

Anti-HAS1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HAS1。Anti-HAS1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB.
别名Hyaluronic acid synthase 1 (HA synthase 1), Hyaluronate synthase 1, Hyaluronan synthase 1, has1
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Cow,Sheep)
验证活性
Sample:
Lane 1: Mouse Testis Lysates
Lane 2: Mouse Spleen Lysates
Lane 3: Rat Testis Lysates
Lane 4: Rat Spleen Lysates
Lane 5: Human U-87 MG cell Lysates
Lane 6: Human DU145 cell Lysates
Primary: Anti-HAS1 (TMAB-00829) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kDa
Observed band size: 65 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein
组织特异性Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Hyaluronan synthase 1
抗原种属
Human
基因名称
HAS1
基因ID
蛋白名称
Hyaluronan synthase 1
Uniprot ID
研究领域
Extracellular Matrix,Stem cells,Axis formation and symmetry,ECM Proteins,Neurogenesis,Other Enzymes
功能
Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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