Name: KSL 128114
Brand: TargetMol
SKU: TP3530
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

待询

50 mg

待询

生物活性

产品描述	KSL 128114 is a syntenin peptide inhibitor that binds to the PDZ1 domain of syntenin with nanomolar affinity. It is resistant to degradation in human plasma and rat liver microsomes and exhibits selectivity for the PDZ domain of syntenin.
体外活性	KSL-128114 (~20 μM) 抑制原发性GBM细胞活力，并在患者来源的异种移植小鼠模型中显著延长生存时间。

化学信息

分子量	2201.59
分子式	C₉₆H₁₆₅N₃₉O₂₁
CAS No.	2757292-12-7
Smiles	C([C@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC(CNC([C@H](NC([C@@H](NC([C@@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CO)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CC(O)=O)=O)C2CCCCC2)=O)[C@](C)(C)C)=O)C=3C=4C(NC3)=CC=CC4
Sequence	Ac-{d-Arg}-Arg-{d-Arg}-Gly-{d-Arg}-Lys-{d-Lys}-Arg-{d-Arg}-Ser-His-Trp-Tle-Chg-Asp-Ile
Sequence Short	RRRGRKKRRSHWXXDI

储存&溶解度

存储	Keep away from moisture Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

KSL 128114