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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NLRP3 Antibody (7L984)

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货号 TMAB-09520

Anti-NLRP3 Antibody (7L984) 是一种 Rabbit 抗体，靶向 NLRP3。Anti-NLRP3 Antibody (7L984) 可用于 ICC/IF。

Anti-NLRP3 Antibody (7L984)

Anti-NLRP3 Antibody (7L984)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09520

Anti-NLRP3 Antibody (7L984) 是一种 Rabbit 抗体，靶向 NLRP3。Anti-NLRP3 Antibody (7L984) 可用于 ICC/IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-NLRP3 Antibody (7L984) is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Antibody (7L984) can be used in ICC/IF.
Ig Type
IgG
克隆号
7L984
反应种属
Human (predicted:Mouse,Rat)
应用ICC/IF
推荐剂量
ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratinizing epithelia of oropharynx, esophagus and ectocervix and in the urothelial layer of the bladder.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis.
抗原信息
免疫原
A synthesized peptide: human NLRP3
抗原种属
Human
基因名称
NLRP3
基因ID
114548
蛋白名称
NACHT, LRR and PYD domains-containing protein 3
Uniprot ID
Q96P20
功能
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
化学信息
分子量Theoretical: 118 kDa. Actual: 118 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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