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顶部生物活性储存和溶解信息计算器

Anti-Phospho-Bad (Ser99) Antibody (7Q57)

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Anti-Phospho-Bad (Ser99) Antibody (7Q57)
产品编号 TMAY-01663
别名 Phospho-Bad (S99), p-Bad (Ser99), p-Bad (S99), BCL2L8, BBC6, BBC2, Bad (p-Ser99), Bad (p-S99), BAD

Anti-Phospho-Bad (Ser99) Antibody (7Q57) 是一种 Rabbit 抗体，靶向 Phospho-Bad (Ser99)。Anti-Phospho-Bad (Ser99) Antibody (7Q57) 可用于 WB。

Anti-Phospho-Bad (Ser99) Antibody (7Q57)
331

Anti-Phospho-Bad (Ser99) Antibody (7Q57)

Rating icon 还可以
Anti-Phospho-Bad (Ser99) Antibody (7Q57)
产品编号 TMAY-01663 别名 Phospho-Bad (S99), p-Bad (Ser99), p-Bad (S99), BCL2L8, BBC6, BBC2, Bad (p-Ser99), Bad (p-S99), BAD

Anti-Phospho-Bad (Ser99) Antibody (7Q57) 是一种 Rabbit 抗体，靶向 Phospho-Bad (Ser99)。Anti-Phospho-Bad (Ser99) Antibody (7Q57) 可用于 WB。

规格价格库存数量
20 μL
¥ 684
5日内发货
100 μL
¥ 1,994
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Bad (Ser99) Antibody (7Q57) is a Rabbit antibody targeting Phospho-Bad (Ser99). Anti-Phospho-Bad (Ser99) Antibody (7Q57) can be used in WB.
别名Phospho-Bad (S99), p-Bad (Ser99), p-Bad (S99), BCL2L8, BBC6, BBC2, Bad (p-Ser99), Bad (p-S99), BAD
Ig Type
Rabbit IgG
克隆号
7Q57
交叉反应
Human
验证活性
1. Western blot analysis of extracts from serum-starved HEK293 overexpressing BAD, untreated(line A) or treated with forskolin (100nM, 30min; +)(line B), using Phospho-Bad (Ser99) rabbit monoclonal Antibody at 1:1000 dilution.
2. Western blot analysis of extracts from serum-starved HEK293 overexpressing BAD, untreated (line A); treated with forskolin (100nM, 30min; +)(line B); treated with forskolin and λ-phosphatase (line C) using Phospho-Bad (Ser99) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment)
应用
WB
推荐剂量
WB: 1:1000-1:20000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Ser99 of Human Phospho-Bad.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景Bcl-2 agonist of cell death (BAD) is a BH3-only member of the Bcl-2 family which possesses important regulatory function in apoptosis. BAD has also been shown to possess many non-apoptotic functions closely linked to cancer including regulation of glycolysis, autophagy, cell cycle progression and immune system development. Oral squamous cell carcinoma (OSCC) is a type of cancer with high morbidity and mortality rates worldwide; it also demonstrates chemotherapeutic resistance. Triterpenoid ursolic acid has been shown to exhibit various biological activities and anticancer effects in several preclinical studies. The apoptosis‑associated signaling showed that ursolic acid decreased the phosphorylation of AKT (Ser473) and B‑cell lymphoma 2 (Bcl‑2)‑associated agonist of cell death (BAD; Ser136), and the protein levels of Bcl‑2 and Bcl‑extra large (Bcl‑xL), and increased the expression of BAD and Bcl‑2‑associated X (Bax) protein in CAR cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: residues around Ser99 of Human Phospho-Bad
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

pBad (Ser99)pBad (S99)Bad (pSer99)Bad (pS99)Bad (phospho-Ser99)Bad (phospho-S99)

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4个月前
5.0
Rating icon 很棒

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