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顶部生物活性储存和溶解信息计算器

Anti-FBXL10 Antibody (6J798)

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Anti-FBXL10 Antibody (6J798)
产品编号 TMAC-01451
别名 Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B

Anti-FBXL10 Antibody (6J798) 是一种 Mouse 抗体，靶向 FBXL10。Anti-FBXL10 Antibody (6J798) 可用于 WB,FCM。

Anti-FBXL10 Antibody (6J798)

Anti-FBXL10 Antibody (6J798)

Rating icon 还可以
Anti-FBXL10 Antibody (6J798)
产品编号 TMAC-01451 别名 Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B

Anti-FBXL10 Antibody (6J798) 是一种 Mouse 抗体，靶向 FBXL10。Anti-FBXL10 Antibody (6J798) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-FBXL10 Antibody (6J798) is a Mouse antibody targeting FBXL10. Anti-FBXL10 Antibody (6J798) can be used in WB,FCM.
别名Protein-containing CXXC domain 2, Protein JEMMA, Protein containing CXXC domain 2, PCCX2, Lysine-specific demethylase 2B, Lysine (K) specific demethylase 2B, KDM2B_HUMAN, kdm2b, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, Jumonji C domain containing histone demethylase 1B, JmjC domain-containing histone demethylation protein 1B, JHDM1B, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, FBXL10, FBXL 10, F-box/LRR-repeat protein 10, F-box protein FBL10, F-box and leucine-rich repeat protein 10, Fbl10, F box protein FBL10, F box and leucine rich repeat protein 10, CXXC-type zinc finger protein 2, CXXC2, [Histone-H3]-lysine-36 demethylase 1B
交叉反应
Human
验证活性
1. Western blot analysis of FBXL10 on human FBXL10 recombinant protein using anti-FBXL10 antibody at 1/1,000 dilution.
2. Western blot analysis of FBXL10 on HEK293 (1) and FBXL10-hIgGFc transfected HEK293 (2) cell lysate using anti-FBXL10 antibody at 1/1,000 dilution.
3. Western blot analysis of FBXL10 on A549 cell lysate using anti-FBXL10 antibody at 1/1,000 dilution.
4. Flow cytometric analysis of Hela cells with FBXL10 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
WB
FCM
推荐剂量
WB: 1:500-1000; FCM: 1:50-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景FBXL10 (F-box and leucine-rich repeat protein 10), also known as Fbl10, CXXC2 (CXXC-type zinc finger protein 2), PCCX2, KDM2B, JEMMA (jumonji domain, EMSY-interactor, methyltransferase motif protein) or JHDM1B (jumonji C domain-containing histone demethylase 1B), is a nuclear protein that contains one F-box domain, a CXXC-type zinc finger, one JMJC domain, four leucine-rich repeats and one PHD-type zinc finger. FBXL10 belongs to the Fbls class of F-box proteins that contain leucine-rich repeats in addition to their F-box motif. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. In addition to its role in substrate recognition as a component of the E3 complex, FBXL10 functions as a dimethylation-specific demethylase, binding iron as a cofactor and demethylating lysine-36 of Histone H3. This suggests that FBXL10 plays a central role in the histone code.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q8NHM5
化学信息
分子量Theoretical: 152 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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