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Anti-TIE1 Antibody (6A314)
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产品编号 TMAC-04040
别名 tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14
Anti-TIE1 Antibody (6A314) 是一种 Mouse 抗体，靶向 TIE1。Anti-TIE1 Antibody (6A314) 可用于 WB,IHC。
Anti-TIE1 Antibody (6A314)
Anti-TIE1 Antibody (6A314)
还可以产品编号 TMAC-04040 别名 tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14
Anti-TIE1 Antibody (6A314) 是一种 Mouse 抗体，靶向 TIE1。Anti-TIE1 Antibody (6A314) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,985 | 5日内发货 | |
| 100 μL | ¥ 2,985 | 5日内发货 |
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| 产品描述 | Anti-TIE1 Antibody (6A314) is a Mouse antibody targeting TIE1. Anti-TIE1 Antibody (6A314) can be used in WB,IHC. |
| 别名 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of TIE1 on human TIE1 recombinant protein using anti-TIE1 antibody at 1/1,000 dilution. 2. Western blot analysis of TIE1 on HEK293 (1) and RAN-hIgGFc transfected HEK293 (2) cell lysate using anti-TIE1 antibody at 1/1,000 dilution. 3. Western blot analysis of TIE1 on HepG2 cell lysate using anti-TIE1 antibody at 1/1,000 dilution. 4. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CD68 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD68 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:200-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Receptor tyrosine kinases play key roles in signal transduction across cell surfaces in biological systems, including the vascular system. These receptors comprise a large and diverse family of catalytically related proteins that, on the basis of sequence and structural similarities, can be divided into several different evolutionary subfamilies. The cloning and characterization of Tie-1 (also designated Tie), a novel human endothelial cell surface receptor tyrosine kinase, has been reported. The extracellular domain of the predicted Tie-1 protein product has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three fibronectin type III repeats next to the transmembrane region. An additional member of this family has been identified as Tie-2 (also designated Tek). Tie-1 and Tie-2 have been shown to be encoded by distinct genes and to represent members of a new class of receptor tyrosine kinases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 125 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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