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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-5HT2C Receptor Antibody (7D349)

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货号 TMAB-02106

Anti-5HT2C Receptor Antibody (7D349) 是一种 Rabbit 抗体，靶向 5HT2C Receptor。Anti-5HT2C Receptor Antibody (7D349) 可用于 WB。

Anti-5HT2C Receptor Antibody (7D349)

Anti-5HT2C Receptor Antibody (7D349)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02106

Anti-5HT2C Receptor Antibody (7D349) 是一种 Rabbit 抗体，靶向 5HT2C Receptor。Anti-5HT2C Receptor Antibody (7D349) 可用于 WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-5HT2C Receptor Antibody (7D349) is a Rabbit antibody targeting 5HT2C Receptor. Anti-5HT2C Receptor Antibody (7D349) can be used in WB.
Ig Type
IgG
克隆号
7D349
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
A synthesized peptide: human 5 HT2C
抗原种属
Human
基因名称
HTR2C
基因ID
3358
蛋白名称
5-hydroxytryptamine receptor 2C
Uniprot ID
P28335
功能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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