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顶部生物活性储存和溶解信息计算器

Anti-SCIN Antibody (4Y852)

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产品编号 TMAH-01073

Anti-SCIN Antibody (4Y852) 是一种抗体，靶向 SCIN。Anti-SCIN Antibody (4Y852) 可用于 ELISA,IHC。

Anti-SCIN Antibody (4Y852)

Anti-SCIN Antibody (4Y852)

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Rating icon 还可以
产品编号 TMAH-01073

Anti-SCIN Antibody (4Y852) 是一种抗体，靶向 SCIN。Anti-SCIN Antibody (4Y852) 可用于 ELISA,IHC。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-SCIN Antibody (4Y852) is an antibody targeting SCIN. Anti-SCIN Antibody (4Y852) can be used in ELISA,IHC.
Ig Type
Rabbit IgG
克隆号
4Y852
交叉反应
Human
验证活性
IHC image of TMAH-01073 diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
应用ELISAIHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cytoplasm, cytoskeleton. Cell projection, podosome.
组织特异性Expressed in megakaryocytes.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts. Regulates chondrocyte proliferation and differentiation. Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human SCIN
抗原种属
Human
基因名称
SCIN
基因ID
85477
Uniprot ID
Q9Y6U3
研究领域
Signal transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

ScinderinSCINKIAA1905KIAA 1905Adseverin

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