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Anti-SCIN Antibody (4Y852)
还可以产品编号 TMAH-01073
Anti-SCIN Antibody (4Y852) 是一种抗体，靶向 SCIN。Anti-SCIN Antibody (4Y852) 可用于 ELISA, IHC。
Anti-SCIN Antibody (4Y852)
Anti-SCIN Antibody (4Y852)
还可以产品编号 TMAH-01073
Anti-SCIN Antibody (4Y852) 是一种抗体，靶向 SCIN。Anti-SCIN Antibody (4Y852) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SCIN Antibody (4Y852) is an antibody targeting SCIN. Anti-SCIN Antibody (4Y852) can be used in ELISA, IHC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 4Y852 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-01073 diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell projection, podosome. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts. Regulates chondrocyte proliferation and differentiation. Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human SCIN |
| 抗原种属 | Human |
| 基因ID | 85477 |
| Uniprot ID | |
| 研究领域 | Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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