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Anti-CXCL9 Antibody-HRP (4K343)

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产品编号 TMAY-01291H

Anti-CXCL9 Antibody-HRP (4K343) 是一种 HRP-conjugated Rabbit 抗体,靶向 CXCL9。Anti-CXCL9 Antibody-HRP (4K343) 可用于 ELISA。

Anti-CXCL9 Antibody-HRP (4K343)

Anti-CXCL9 Antibody-HRP (4K343)

Rating icon 还可以
产品编号 TMAY-01291H

Anti-CXCL9 Antibody-HRP (4K343) 是一种 HRP-conjugated Rabbit 抗体,靶向 CXCL9。Anti-CXCL9 Antibody-HRP (4K343) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-CXCL9 Antibody-HRP (4K343) is a HRP-conjugated Rabbit antibody targeting CXCL9. Anti-CXCL9 Antibody-HRP (4K343) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
4K343
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CXCL9 / MIG (rh CXCL9 / MIG; TMPY-02234; Q07325; Thr23-Thr125), and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined; however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. Experiment data represent novel mechanisms by which tumour cells in melanoma metastases might use the chemokine-expressing endothelium to leave the tumour and eventually to form additional metastases at distinct sites. Experiment results also improved that CXCL9/MIG plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9/MIG, and recipient CD4 lymphocytes are necessary for sustained CXCL9/MIG production and CAV development in this model. Neutralization of the chemokine CXCL9/MIG may have therapeutic potential for the treatment of chronic rejection after heart transplantation.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human CXCL9 / MIG protein (TMPY-02234)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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