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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SP140 Polyclonal Antibody

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货号 TMAB-13073

Anti-SP140 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SP140。Anti-SP140 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SP140 Polyclonal Antibody

Anti-SP140 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13073

Anti-SP140 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SP140。Anti-SP140 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-SP140 Polyclonal Antibody is a Rabbit antibody targeting SP140. Anti-SP140 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Localized to nuclear structures termed LANDS, for LYSp100-associated nuclear domains. LANDS are globular, electron-dense structures most often found in the nucleoplasm, but also found at the nuclear membrane and in the cytoplasm, suggesting that these structures may traffic between the cytoplasm and the nucleus.
组织特异性High levels in spleen and peripheral blood leukocytes, much lower levels in thymus, prostate, ovary, small intestine, and colon. Very low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SP140 is an 867 amino acid cytoplasmic and nuclear protein that is highly expressed in spleen and peripheral blood leukocytes. SP140 is a component of the nuclear body that may be involved in trafficking between the nucleus and the cytoplasm. SP140 is induced by interferons and contains a bromo domain, a HSR domain, a PHD-type zinc finger and a SAND domain. It is thought that SP140 may participate in the pathogenesis of acute promyelocytic leukemia and viral infection. SP140 is expressed as three isoforms produced by alternative splicing and are designated isoform LYSp100-A, isoform LYSp100-B and isoform SP140.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse SP140
抗原种属
Mouse
基因名称
SP140
基因ID
11262
蛋白名称
Nuclear body protein SP140
功能
Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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