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Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2
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还可以产品编号 TMAB-10378
Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Bcl2 (Ser87)。Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2
Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-10378
Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Bcl2 (Ser87)。Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Bcl2 (Ser87). Anti-Phospho-Bcl2 (Ser87) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 交叉反应 | Human,Rat (predicted:Mouse,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. |
| 组织特异性 | Expressed in a variety of tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8). |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human Bcl2 around the phosphorylation site of Ser87 |
| 抗原种属 | Human |
| 基因名称 | BCL2 |
| 基因ID | |
| 蛋白名称 | Apoptosis regulator Bcl-2 |
| Uniprot ID | |
| 功能 | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
| 分子量 | Theoretical: 26 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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