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Anti-IL-18R beta/IL-18RAP Antibody (7B376)
还可以产品编号 TMAY-00410
Anti-IL-18R beta/IL-18RAP Antibody (7B376) 是一种 Rabbit 抗体，靶向 IL-18R beta/IL-18RAP。Anti-IL-18R beta/IL-18RAP Antibody (7B376) 可用于 WB,ELISA。
Anti-IL-18R beta/IL-18RAP Antibody (7B376)
Anti-IL-18R beta/IL-18RAP Antibody (7B376)
还可以产品编号 TMAY-00410
Anti-IL-18R beta/IL-18RAP Antibody (7B376) 是一种 Rabbit 抗体，靶向 IL-18R beta/IL-18RAP。Anti-IL-18R beta/IL-18RAP Antibody (7B376) 可用于 WB,ELISA。
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| 产品描述 | Anti-IL-18R beta/IL-18RAP Antibody (7B376) is a Rabbit antibody targeting IL-18R beta/IL-18RAP. Anti-IL-18R beta/IL-18RAP Antibody (7B376) can be used in WB,ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7B376 |
| 交叉反应 | Human |
| 验证活性 | Anti-IL1R7 rabbit monoclonal antibody at 1:500 dilution. -Lane A: RAW264.7 Whole Cell Lysate. -Lane B: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:68 kDa. -Observed band size:75 kDa |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL18RAP/IL1R7 (rh IL18RAP/IL1R7; TMPY-01446; NP_003844.1; Met1-Gly357). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand-binding subunit of the IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. IL18RAP is required for the high-affinity binding of interleukin 18 (IL-18) to its receptor complex. IL18RAP together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. Two putative isoforms of IL18RAP were detected and the ratios and total levels of these isoforms may contribute to the etiology of coeliac disease. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity, and atopic asthma. Analysis of IL18R1 and IL18RAP SNPs in 5 European prospective cohorts suggests that the variability of these genes are unlikely to contribute to modulate the risk of CVD in European populations. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL18RAP/IL1R7 Protein (TMPY-01446) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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