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顶部生物活性储存和溶解信息计算器

Anti-LYVE1 Antibody (3Z624)

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Anti-LYVE1 Antibody (3Z624)
产品编号 TMAC-02440
别名 XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1

Anti-LYVE1 Antibody (3Z624) 是一种 Rabbit 抗体，靶向 LYVE1。Anti-LYVE1 Antibody (3Z624) 可用于 WB,ICC/IF,IHC,FCM。

Anti-LYVE1 Antibody (3Z624)

Anti-LYVE1 Antibody (3Z624)

Rating icon 还可以
Anti-LYVE1 Antibody (3Z624)
产品编号 TMAC-02440 别名 XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1

Anti-LYVE1 Antibody (3Z624) 是一种 Rabbit 抗体，靶向 LYVE1。Anti-LYVE1 Antibody (3Z624) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-LYVE1 Antibody (3Z624) is a Rabbit antibody targeting LYVE1. Anti-LYVE1 Antibody (3Z624) can be used in WB,ICC/IF,IHC,FCM.
别名XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of LYVE1 on MCF-7 lysates using anti-LYVE1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-LYVE1 antibody. Counter stained with hematoxylin.
3. ICC staining LYVE1 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining LYVE1 in HUVEC cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining LYVE1 in SW480 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of HUVEC cells with LYVE1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
IHC
FCM
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) is expressed on the cell surface as a protein that is reduced by glycosidase treatment. LYVE-1 is abundant in spleen, lymph node, heart, lung and fetal liver, and is less abundant in appendix, bone marrow, placenta, muscle and adult liver. Expression of LYVE-1 is largely restricted to endothelial cells lining lymphatic vessels and splenic sinusoidal endothelial cells. LYVE-1 binds to both soluble and immobilized hyaluronan (HA) with greater specificity than HCAM. Like HCAM, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike HCAM, the LYVE-1 molecule co-localizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. LYVE-1 is used as a marker to study tumor lymphangiogenesis, which is an important area of investigation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9Y5Y7
化学信息
分子量Theoretical: 35 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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