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Anti-Phospho-Src (Tyr530) Antibody (5Q242)
还可以产品编号 TMAY-01694
Anti-Phospho-Src (Tyr530) Antibody (5Q242) 是一种 Rabbit 抗体，靶向 Phospho-Src (Tyr530)。Anti-Phospho-Src (Tyr530) Antibody (5Q242) 可用于 WB。
Anti-Phospho-Src (Tyr530) Antibody (5Q242)
Anti-Phospho-Src (Tyr530) Antibody (5Q242)
还可以产品编号 TMAY-01694
Anti-Phospho-Src (Tyr530) Antibody (5Q242) 是一种 Rabbit 抗体，靶向 Phospho-Src (Tyr530)。Anti-Phospho-Src (Tyr530) Antibody (5Q242) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-Src (Tyr530) Antibody (5Q242) is a Rabbit antibody targeting Phospho-Src (Tyr530). Anti-Phospho-Src (Tyr530) Antibody (5Q242) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5Q242 |
| 交叉反应 | Human; Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Chicken, Zebrafish |
| 验证活性 | 1. Western blot analysis of extracts from serum-starved Jurkat, untreated(line A) or treated with H2O2(2mM, 2min; +)(line B), using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:2000 dilution (upper) or Anti-Actin Antibody, Chimeric Rabbit Monoclonal at 1:50000 dilution (lower). 2. Western blot analysis of extracts from serum-starved Jurkat, untreated (line A); treated with H2O2(2mM, 2min; +) (line B); treated with H2O2and λ-phosphatase (line C) using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) 3. Western blot analysis of extracts from serum-starved Jurkat treated with H2O2(2mM, 2min), using Phospho-Src (Tyr530) rabbit monoclonal Antibody at 1:10000, 1:50000, 1:200000 dilution. (Validation Experiment) |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around (Tyr530) of Human Phospho-Src. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the residues around (Tyr530) of Human Phospho-Src |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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