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Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

Synonyms: PTA, FXI, F11, Coagulation factor XI
货号 TMPK-01271 一键复制产品信息
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Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-01271

别名 PTA, FXI, F11, Coagulation factor XI

Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)
规格价格库存数量
5 μg
¥ 358
6-8日内发货
10 μg
¥ 573
6-8日内发货
20 μg
¥ 938
5日内发货
50 μg
¥ 1,830
5日内发货
100 μg
¥ 3,100
5日内发货
200 μg
¥ 5,620
5日内发货
500 μg
¥ 12,400
5日内发货
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产品介绍


生物活性
产品描述
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
生物活性
Immobilized Cynomolgus Coagulation factor XI, His Tag at 0.5 μg/mL (100 μL/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 4.9 ng/mL determined by ELISA (QC Test).
研究背景
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
种属
Cynomolgus
表达系统
HEK293 Cells
标签C-His
蛋白编号XP_005556540.2
蛋白构建Glu44-Ala650
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
别名PTA, FXI, F11, Coagulation factor XI
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量69.05 kDa (predicted). Due to glycosylation, the protein migrates to 70-85 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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剂量转换

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