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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CEACAM1 Antibody-APC (7F98)

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货号 TMAY-01215A

别名 CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP

Anti-CEACAM1 Antibody-APC (7F98) 是一种 APC-conjugated Mouse 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody-APC (7F98) 可用于 FCM。

Anti-CEACAM1 Antibody-APC (7F98)

Anti-CEACAM1 Antibody-APC (7F98)

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Rating icon 还可以
货号 TMAY-01215A 别名 CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP

Anti-CEACAM1 Antibody-APC (7F98) 是一种 APC-conjugated Mouse 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody-APC (7F98) 可用于 FCM。

规格价格库存数量
25 T
¥ 895
5日内发货
100 T
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-CEACAM1 Antibody-APC (7F98) is a APC-conjugated Mouse antibody targeting CEACAM1. Anti-CEACAM1 Antibody-APC (7F98) can be used in FCM.
别名CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Ig Type
Mouse IgG1
克隆号
7F98
反应种属
Human
特异性
Human CEACAM-1/CD66a
验证活性
Flow cytometric analysis of Human CEACAM1(CD66a) expression on HT29 cells. Cells were stained with APC-conjugated anti-Human CEACAM1(CD66a). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
2 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM1 / CD66a (rh CEACAM1 / CD66a; TMPY-00717; NP_001020083.1; Met1-Gly428) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human CEACAM1 / CD66a Protein (TMPY-00717)
抗原种属
Human
研究领域
Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules
储存&溶解度
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.
存储keep away from direct sunlight | 4°C for 1 year

计算器

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关键词

biliary glycoproteinBGP-1BGP 1
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