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HRSP12 Protein, Human, Recombinant (His)
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还可以货号 TMPJ-01007
别名 UK114 Antigen Homolog, Ribonuclease UK114, PSP, p14.5, HRSP12, Heat-Responsive Protein 12, 14.5 kDa Translational Inhibitor Protein
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
其他形式的 “HRSP12 Protein, Human, Recombinant (His)”:
HRSP12 Protein, Human, Recombinant (His)
一键复制产品信息 还可以货号 TMPJ-01007 别名 UK114 Antigen Homolog, Ribonuclease UK114, PSP, p14.5, HRSP12, Heat-Responsive Protein 12, 14.5 kDa Translational Inhibitor Protein
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 385 | 6-8日内发货 | |
| 10 μg | ¥ 620 | 6-8日内发货 | |
| 20 μg | ¥ 956 | 5日内发货 | |
| 50 μg | ¥ 1,720 | 5日内发货 | |
| 100 μg | ¥ 2,970 | 5日内发货 | |
| 200 μg | ¥ 5,530 | 5日内发货 | |
| 500 μg | ¥ 12,100 | 5日内发货 | |
| 1 mg | ¥ 17,300 | 5日内发货 |
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| 产品描述 | Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6xHis |
| 蛋白编号 | P52758 |
| 氨基酸序列 | Met1-Leu137 |
| 蛋白构建 | Met1-Leu137 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, 10% Glycerol, pH 8.0. |
| 别名 | UK114 Antigen Homolog, Ribonuclease UK114, PSP, p14.5, HRSP12, Heat-Responsive Protein 12, 14.5 kDa Translational Inhibitor Protein |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 16 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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