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Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
Synonyms: LERK5, HTKL, EPLG5, Ephrin B2, EFNB2货号 TMPK-00223 一键复制产品信息
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Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells.
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00223
别名 LERK5, HTKL, EPLG5, Ephrin B2, EFNB2
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells.
其他形式的 “Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)”:
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 178 | 现货 | |
| 10 μg | ¥ 268 | 现货 | |
| 20 μg | ¥ 418 | 现货 | |
| 50 μg | ¥ 797 | 现货 | |
| 100 μg | ¥ 1,320 | 现货 | |
| 200 μg | ¥ 2,390 | 5日内发货 | |
| 500 μg | ¥ 5,330 | 5日内发货 |
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纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
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产品介绍
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| 产品描述 | Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells. |
| 生物活性 | Immobilized Human EPHB2, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Human Ephrin-B2, hFc Tag with the EC50 of 3.2 ng/mL determined by ELISA (QC Test). Human Ephrin-B2, hFc Tag captured on CM5 Chip via Protein A can bind Human EPHB2, His Tag with an affinity constant of 82.97 pM as determined in SPR assay (Biacore T200). |
| 研究背景 | Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc |
| 蛋白编号 | P52799 |
| 蛋白构建 | Ile28-Ala229 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | LERK5, HTKL, EPLG5, Ephrin B2, EFNB2 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 49 kDa (predicted). Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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