生物活性

产品描述	Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045219762.1.
生物活性	Human LIF R, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus OSM, His Tag with an affinity constant of 1.31 μM as determined in SPR assay (Biacore T200).
研究背景	OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	XP_0452197621
蛋白构建	Ala27-Arg221
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	23.31 kDa (Predicted); 27-50 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His)

Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His)

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