Phenazine-1-carboxylic acid

Name: Phenazine-1-carboxylic acid
Brand: TargetMol
SKU: TN7105
Price: 168 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.61%

货号 TN7105Cas号 2538-68-3

别名 吩嗪-1-羧酸

Phenazine-1-carboxy acid 对所有植物病原真菌均显示出很强的抗真菌活性，抑制真菌生长约 90-100%。

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Phenazine-1-carboxylic acid

一键复制产品信息

很棒

纯度: 99.61%

货号 TN7105 别名 吩嗪-1-羧酸Cas号 2538-68-3

Phenazine-1-carboxy acid 对所有植物病原真菌均显示出很强的抗真菌活性，抑制真菌生长约 90-100%。

规格	价格	库存
5 mg	¥ 168	现货
10 mg	¥ 227	现货
25 mg	¥ 353	现货
50 mg	¥ 497	现货
100 mg	¥ 747	现货
500 mg	¥ 1,790	现货

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纯度: 99.61%

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COA HNMR HPLC 产品操作手册

产品介绍

Phenazine-1-carboxylic acid AI Summary

Phenazine-1-carboxylic acid exhibits a broad spectrum of bioactivities including antibacterial effects against Bacillus cereus (MIC < 0.5 µg/mL), Micrococcus luteus (MIC < 5.0 µg/mL), and Staphylococcus aureus (MIC < 5.0 µg/mL) observed through disk assay over 2 days. It also demonstrates antibacterial activity against methicillin-resistant Staphylococcus aureus, Mycobacterium fortuitum, Mycobacterium aurum, Mycobacterium vaccae, and Mycobacterium smegmatis with MIC values ranging from 25.0 to 100.0 µg/mL. Additionally, it inhibits Mycobacterium tuberculosis H37Rv ATCC 27292 with a MIC90 of 32.9 µg/mL, as determined using the Alamar blue assay. The compound displays substantial antifungal properties, inhibiting the mycelial growth of various fungal strains such as Botryosphaeria berengeriana, Fusarium spp., Mycosphaerella arachidis, Alternaria solani, and Colletotrichum falcatum, with EC50 values ranging from 3.58 to 18.5 µg/mL and an inhibition zone of 2.0 mm at 100 µg/disc after 10 to 15 days. Furthermore, Phenazine-1-carboxylic acid shows diverse bioactivities in multiple assays, including inhibition of ALDH1A1, influenza NS1 protein function, TGF-β, and inducing DNA re-replication in colon adenocarcinoma cells. However, it has no significant activity against human AChE, Bacillus subtilis DSM 347, or KIF5 cells, with IC50 values greater than 50000 nM. It also exhibits cytotoxicity against HCT116 cells with an IC50 value of 15600 nM after 5 days..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Phenazine-1-carboxylic acid shows strong antifungal activity against all phytopathogenic fungi, inhibiting the fungal growth by about 90-100%. Phenazine-1-carboxylic acid could be used to compete with other phytopathogenic fungi that attack grapevine
别名	吩嗪-1-羧酸

化学信息

分子量	224.21
分子式	C₁₃H₈N₂O₂
CAS No.	2538-68-3
Smiles	OC(=O)c1cccc2nc3ccccc3nc12
密度	No data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 5 mg/mL (22.3 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4601 mL	22.3005 mL	44.6010 mL	223.0052 mL
5 mM	0.8920 mL	4.4601 mL	8.9202 mL	44.6010 mL
10 mM	0.4460 mL	2.2301 mL	4.4601 mL	22.3005 mL
20 mM	0.2230 mL	1.1150 mL	2.2301 mL	11.1503 mL