Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1].
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,190 | 现货 | ||
5 mg | ¥ 2,970 | 现货 | ||
10 mg | ¥ 4,380 | 现货 | ||
25 mg | ¥ 6,860 | 现货 | ||
50 mg | ¥ 9,450 | 现货 | ||
100 mg | ¥ 12,700 | 现货 | ||
500 mg | ¥ 25,500 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 3,280 | 现货 |
产品描述 | PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1]. |
体外活性 | The high concentrations (10 μM and 100 μM) of PI-55 lead to an incomplete blocking of early haustorial structure development, especially when cytokinin activity promotes it. PI-55 treatment also reduces the overall aggressiveness of P. ramosa when applied with BAP in comparison with BAP alone, suggesting that the signaling pathway leading to early haustorial structure formation involves histidine kinase receptors homologous to CRE1/AHK4 and AHK3 [1]. |
别名 | 6-(2-hydroxy-3-methylbenzylamino)purine |
分子量 | 255.28 |
分子式 | C13H13N5O |
CAS No. | 1122579-42-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11.7 mg/mL (45.8 mM), Sonication and heating to 70℃ are recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.9173 mL | 19.5863 mL | 39.1727 mL | 97.9317 mL |
5 mM | 0.7835 mL | 3.9173 mL | 7.8345 mL | 19.5863 mL | |
10 mM | 0.3917 mL | 1.9586 mL | 3.9173 mL | 9.7932 mL | |
20 mM | 0.1959 mL | 0.9793 mL | 1.9586 mL | 4.8966 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
PI-55 1122579-42-3 Others PI55 PI 55 6-(2-hydroxy-3-methylbenzylamino)purine Inhibitor inhibitor inhibit