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Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IkappaB- beta (Ser23)。Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-IkappaB- beta (Ser23)。Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IkappaB- beta (Ser23). Anti-Phospho-IkappaB- beta (Ser23) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-IkappaB- beta (Ser23), p-IkappaB- beta (S23), IkappaB- beta (p-Ser23), IkappaB- beta (p-S23) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-b (Phospho-Ser23) Antibody TMAC-02120 (left) or the same antibody preincubated with blocking peptide (right). 2. Western blot analysis of extracts from HT29 cells, treated with CA or calf intestinal phosphatase (CIP), using IkB-b (Phospho-Ser23) Antibody TMAC-02120. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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