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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-Neuropilin-2 Antibody (3D949)

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货号 TMAY-01078

别名 Npn-2, Npn2, Np-2, Np2, neuropilin 2, 1110048P06Rik

Anti-Neuropilin-2 Antibody (3D949) 是一种 Mouse 抗体，靶向 Neuropilin-2。Anti-Neuropilin-2 Antibody (3D949) 可用于 ELISA(Cap)。

Anti-Neuropilin-2 Antibody (3D949)

Anti-Neuropilin-2 Antibody (3D949)

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Rating icon 还可以
货号 TMAY-01078 别名 Npn-2, Npn2, Np-2, Np2, neuropilin 2, 1110048P06Rik

Anti-Neuropilin-2 Antibody (3D949) 是一种 Mouse 抗体，靶向 Neuropilin-2。Anti-Neuropilin-2 Antibody (3D949) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 585
5日内发货
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-Neuropilin-2 Antibody (3D949) is a Mouse antibody targeting Neuropilin-2. Anti-Neuropilin-2 Antibody (3D949) can be used in ELISA(Cap).
别名Npn-2, Npn2, Np-2, Np2, neuropilin 2, 1110048P06Rik
Ig Type
Mouse IgG2b
克隆号
3D949
反应种属
Human
特异性
Human Neuropilin-2/NRP2
应用ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NRP2 / Neuropilin-2 (rh NRP2 / Neuropilin-2; TMPY-00892; NP_003863.2; Met1-Tyr855). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellular signaling pathways via interacting with other cell surface receptors such as VEGF receptors and plexins. NRP-2 is well known for its role in facilitating axonal guidance during the development of the neuronal system, and additionally, it is also expressed in vascular endothelial cells and lymphatic endothelium where it affects proliferation, migration, angiogenesis, as well as the formation of small lymphatic vessels and capillaries. A recent study has identified NRP-2 as a polysialylation protein expressed in human dendritic cells and modulates DC-T Cell Interactions. Nearly all tumor cells express neuropilins and NRP-2 is predominantly expressed in neuronal tumors and melanomas. Furthermore, it is suggested that as the specific ligand for NRP-2, SEMA 3F inhibits tumor angiogenesis, and metastasis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human NRP2 / Neuropilin-2 Protein (TMPY-00892)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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