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Anti-CD59 Antibody (3N749)
还可以产品编号 TMAY-02363
Anti-CD59 Antibody (3N749) 是一种 Rabbit 抗体，靶向 CD59。Anti-CD59 Antibody (3N749) 可用于 ELISA,FCM。
Anti-CD59 Antibody (3N749)
Anti-CD59 Antibody (3N749)
还可以产品编号 TMAY-02363
Anti-CD59 Antibody (3N749) 是一种 Rabbit 抗体，靶向 CD59。Anti-CD59 Antibody (3N749) 可用于 ELISA,FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD59 Antibody (3N749) is a Rabbit antibody targeting CD59. Anti-CD59 Antibody (3N749) can be used in ELISA,FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3N749 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD59 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD59, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD59 (rh CD59; TMPY-02019; P13987-1; Met 1-Glu 101). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/PerCP/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human CD59 protein (TMPY-02019) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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