规格

价格

库存

数量

1 mg

¥ 867

现货

2 mg

¥ 1,290

现货

5 mg

¥ 1,990

现货

10 mg

¥ 2,990

现货

25 mg

¥ 4,950

现货

50 mg

¥ 6,910

现货

1 mL x 10 mM (in DMSO)

¥ 1,860

现货

生物活性

产品描述	Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.
靶点活性	Antiplasmodial:5.80 μM, DPPH:54.53 ug/mL
体外活性	Atherosperminine对抗恶性疟原虫(Plasmodium falciparum)表现出强大的抗疟疾活性，其半抑制浓度(IC50)为5.80 μM。此外，Atherosperminine在DPPH实验中亦展示了抗氧化活性，IC50值达到54.53 ug/mL[3]。
别名	芒籽宁

化学信息

分子量	309.4
分子式	C₂₀H₂₃NO₂
CAS No.	5531-98-6
Smiles	O(C)C=1C=2C(C(CCN(C)C)=CC1OC)=CC=C3C2C=CC=C3
密度	1.109 g/cm3 (Predicted)
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (161.6 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2321 mL	16.1603 mL	32.3206 mL	161.6031 mL
5 mM	0.6464 mL	3.2321 mL	6.4641 mL	32.3206 mL
10 mM	0.3232 mL	1.6160 mL	3.2321 mL	16.1603 mL
20 mM	0.1616 mL	0.8080 mL	1.6160 mL	8.0802 mL
50 mM	0.0646 mL	0.3232 mL	0.6464 mL	3.2321 mL
100 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6160 mL