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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BLM Polyclonal Antibody 2

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货号 TMAB-03154

Anti-BLM Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 BLM。Anti-BLM Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-BLM Polyclonal Antibody 2

Anti-BLM Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-03154

Anti-BLM Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 BLM。Anti-BLM Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-BLM Polyclonal Antibody 2 is a Rabbit antibody targeting BLM. Anti-BLM Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Bloom’s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, sun sensitivity, immunodeficiency and a predisposition to various cancers. The gene responsible for Bloom’s syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom’s syndrome patients. One characteristic of Bloom’s syndrome is an increased frequency of sister chromatid exchange (SCE). BLM has been shown to unwind G4 DNA, and a failure of this function is thought to be responsible for the increased rate of SCE. BLM is known to be translocated to the nucleus, where its ATPase activity is stimulated by both single- and double-stranded DNA. Mutations in the yeast SGS1, a homolog of BLM, are known to cause mitotic hyperrecombination similiar to that observed in Bloom’s cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BLM
抗原种属
Human
基因名称
BLM
基因ID
641
蛋白名称
RecQ-like DNA helicase BLM
Uniprot ID
P54132
功能
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.
化学信息
分子量Theoretical: 159 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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