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Anti-TNF beta Antibody (4P839)
还可以产品编号 TMAY-00541
Anti-TNF beta Antibody (4P839) 是一种 Mouse 抗体，靶向 TNF beta。Anti-TNF beta Antibody (4P839) 可用于 ELISA,ELISA(Cap)。
Anti-TNF beta Antibody (4P839)
Anti-TNF beta Antibody (4P839)
还可以产品编号 TMAY-00541
Anti-TNF beta Antibody (4P839) 是一种 Mouse 抗体，靶向 TNF beta。Anti-TNF beta Antibody (4P839) 可用于 ELISA,ELISA(Cap)。
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抗原信息
| 产品描述 | Anti-TNF beta Antibody (4P839) is a Mouse antibody targeting TNF beta. Anti-TNF beta Antibody (4P839) can be used in ELISA,ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4P839 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Cap) |
| 推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu 35-Leu 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| 研究背景 | Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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