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Anti-TNF beta Antibody (4P839)

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Anti-TNF beta Antibody (4P839)
产品编号 TMAY-00541
别名 肿瘤坏死因子, TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT

Anti-TNF beta Antibody (4P839) 是一种 Mouse 抗体,靶向 TNF beta。Anti-TNF beta Antibody (4P839) 可用于 ELISA,ELISA(Cap)。

Anti-TNF beta Antibody (4P839)
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Anti-TNF beta Antibody (4P839)

Rating icon 还可以
Anti-TNF beta Antibody (4P839)
产品编号 TMAY-00541 别名 肿瘤坏死因子, TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT

Anti-TNF beta Antibody (4P839) 是一种 Mouse 抗体,靶向 TNF beta。Anti-TNF beta Antibody (4P839) 可用于 ELISA,ELISA(Cap)。

规格价格库存数量
20 μL
¥ 585
5日内发货
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNF beta Antibody (4P839) is a Mouse antibody targeting TNF beta. Anti-TNF beta Antibody (4P839) can be used in ELISA,ELISA(Cap).
别名肿瘤坏死因子, TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Ig Type
Mouse IgG1
克隆号
4P839
交叉反应
Human
应用
ELISA,ELISA(Cap)
推荐剂量
ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu 35-Leu 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
研究背景Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153)
抗原种属
Human
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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