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IL-15 Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P40933.

| 规格 | 价格 | 库存 | 数量 |
|---|
| 生物活性 | ED 50 < 0.5 ng/ml, determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells, corresponding to a specific activity of > 2.0 × 10^6 units/mg. |
| 产品描述 | IL-15 Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P40933. |
| 种属 | Human |
| 表达系统 | E. coli |
| 蛋白编号 | P40933 |
| 别名 | 白介素,interleukin 15,IL-15 |
| 蛋白构建 | Asn49-Ser162 Expressed with an N-terminal Met |
| 蛋白纯度 | > 95% as determined by SDS-PAGE |
| 分子量 | 13.6 kDa (Reducing conditions) |
| 内毒素 | < 0.2 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Interleukin-15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (among other cells) following infection by virus. This cytokine induces cell proliferation of natural killer cells, which are cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 can stimulate the proliferation of T-lymphocytes. Stimulation by IL-15 occurs following its interaction with IL-15Rα. This interaction may enhance IL-15’s interaction with IL15Rβγc. |