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Anti-NCKIPSD Polyclonal Antibody

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货号 TMAB-09280

Anti-NCKIPSD Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NCKIPSD。Anti-NCKIPSD Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NCKIPSD Polyclonal Antibody

Anti-NCKIPSD Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09280

Anti-NCKIPSD Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NCKIPSD。Anti-NCKIPSD Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-NCKIPSD Polyclonal Antibody is a Rabbit antibody targeting NCKIPSD. Anti-NCKIPSD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Pig,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
组织特异性Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human NCKIPSD
抗原种属
Human
基因名称
NCKIPSD
基因ID
蛋白名称
NCK-interacting protein with SH3 domain
Uniprot ID
功能
Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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