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Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-eIF4EBP1 (Thr70)。Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-eIF4EBP1 (Thr70)。Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody is a Rabbit antibody targeting Phospho-eIF4EBP1 (Thr70). Anti-Phospho-eIF4EBP1 (Thr70) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse,Sheep) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Lung and testis. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human EIF4B around the phosphorylation site of Thr70 |
| 抗原种属 | Human |
| 基因名称 | EIF4EBP1 |
| 基因ID | |
| 蛋白名称 | Eukaryotic translation initiation factor 4E-binding protein 1 |
| Uniprot ID | |
| 功能 | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| 分子量 | Theoretical: 12 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |