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顶部生物活性储存和溶解信息计算器

Anti-Phospho-ATF2 (Thr71) Antibody (3X852)

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产品编号 TMAC-03192

别名 p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71)

Anti-Phospho-ATF2 (Thr71) Antibody (3X852) 是一种 Rabbit 抗体，靶向 Phospho-ATF2 (Thr71)。Anti-Phospho-ATF2 (Thr71) Antibody (3X852) 可用于 WB,ICC/IF,IP。

Anti-Phospho-ATF2 (Thr71) Antibody (3X852)

Anti-Phospho-ATF2 (Thr71) Antibody (3X852)

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Rating icon 还可以
产品编号 TMAC-03192 别名 p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71)

Anti-Phospho-ATF2 (Thr71) Antibody (3X852) 是一种 Rabbit 抗体，靶向 Phospho-ATF2 (Thr71)。Anti-Phospho-ATF2 (Thr71) Antibody (3X852) 可用于 WB,ICC/IF,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ATF2 (Thr71) Antibody (3X852) is a Rabbit antibody targeting Phospho-ATF2 (Thr71). Anti-Phospho-ATF2 (Thr71) Antibody (3X852) can be used in ICC/IF,IP,WB.
别名p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71)
Ig Type
IgG
克隆号
3X852
交叉反应
Human
验证活性
1. ICC staining phospho-ATF2 (T71) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining phospho-ATF2 (T71) in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining phospho-ATF2 (T71) in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
应用ICC/IFIPWB
推荐剂量
WB: 1:1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular cis-acting promotor and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The ATF/CREB family includes CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr 69 and Thr 71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr 69 and Thr 71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro. The gene encoding human ATF-2 maps to chromosome 2q31.1.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human ATF2 around the phosphorylation site of Thr71
抗原种属
human
Uniprot ID
Q07954
化学信息
分子量Theoretical: 55 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pATF2 (Thr71)pATF2 (T71)ATF2 (pThr71)ATF2 (pT71)ATF2 (phospho-Thr71)ATF2 (phospho-T71)

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